Prevalence:

• 1 in 2,000 fetuses at 20 weeks’ gestation.

Ultrasound diagnosis:

• Presence of solitary or multiple echogenic foci (1-2 mm in diameter) within the substance of the liver or in the capsule.

Associated abnormalities:

• The incidence of chromosomal abnormalities and genetic syndroms is not increased.
• Parenchymal calcifications may be due to intrauterine infection.

Investigations:

• Detailed ultrasound examination.
• TORCH test for fetal infections.

Follow up:

• In isolated cases follow-up should be standard.

Delivery:

• Standard obstetric care and delivery.

Prognosis:

• Good.

Recurrence:

• No increased risk of recurrence.