This application allows estimation of risks of early-PE (delivery at <32 weeks gestation), preterm-PE (<37 weeks) and term-PE (≥37 weeks) by a combination of maternal factors and results of various biophysical and biochemical measurements made at different stages in pregnancy.

Risk calculation is provided for the gestational age blocks of 11+0 to 14+1, 19+0 to 24+6, 30+0 to 34+6 and 35+0 to 37+6 weeks. Please note that when using biophysical and biochemical markers the measurements should be obtained within the same gestational age block.

  • Useful markers in the first trimester (11+0 to 14+1 weeks) are MAP, UTPI, PLGF and PAPP-A PDF1, PDF2.
  • Useful markers in the second trimester (19+0 to 24+6 weeks) are MAP, UTPI, PLGF and sFLT-1 PDF3.
  • Useful markers in the third trimester are MAP, UTPI, PLGF and sFLT-1 PDF4, PDF5.

For more information on the background of this application please click here.

This software is based on research carried out by The Fetal Medicine Foundation. Neither the FMF​ nor any other party involved in the development of this software shall be held liable for results produced using data from unconfirmed sources. Clinical risk assessment requires that the ultrasound and biochemical measurements are taken and analyzed by accredited practitioners and laboratories.


Maternal factors

Maternal characteristics

cm
ft
in
kg
lbs
 
 
 

Pregnancy dating (select one of the methods below)

mm
weeks
days
weeks
 

Medical history

Obstetric history


This application allows calculation of risks for PE based on maternal factors alone and in combination with any of the biomarkers. Biophysical and biochemical markers should be obtained within the same gestational age block (11+0 to 14+1, 19+0 to 24+6, 30+0 to 34+6, 35+0 to 37+6 weeks).

Biophysical measurements

Useful markers for all three trimesters are MAP and mean UTPI
Date of measurement Weight MAP (mmHg) Mean UTPI  
kg
lbs
 

Biochemical measurements

Useful markers in the first trimester are PLGF and PAPP-A and in the second and third trimesters are PLGF and sFLT-1
Date of measurement Weight PLGF (MoM) PAPP-A (MoM) sFLT-1 (MoM)  
kg
lbs
 

Measurement 1
  Left arm Right arm
Systolic
Diastolic
Measurement 2
  Left arm Right arm
Systolic
Diastolic
Left
Right
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