Fetal abnormalities » Brain
- 1 in 10,000 births.
- Absent cavum septum pellucidum with communicating frontal horns.
- The incidence of chromosomal abnormalities and genetic syndromes is not increased.
- In septo-optic dysplasia, in addition to absent cavum septum pellucidum, there is hypoplasia of the optic nerves and / or hypothalamic-pituitary abnormalities.
- Detailed ultrasound examination, including neurosonography.
- Fetal brain MRI to assess optic nerves and chiasm, hypothalamic-pituitary gland, and to demonstrate possible associated cortical abnormalities (polymicrogyria and schizencephaly).
- Follow-up should be standard.
- Standard obstetric care and delivery.
- Isolated absent cavum septum pellucidum: usually asymptomatic.
- Septo-optic dysplasia: visual disturbances may range from blindness to almost normal vision. Hormone insufficiencies can be treated with hormone replacement therapy.
- No increased risk of recurrence.