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Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection.
Lo YM, Tsui NB, Chiu RW, Lau TK, Leung TN, Heung MM, Gerovassili A, Jin Y, Nicolaides KH, Cantor CR, Ding C.
Nat Med 2007;13:218-23. -
Free fetal DNA in maternal circulation: a potential prognostic marker for chromosomal abnormalities?
Gerovassili A, Garner C, Nicolaides KH, Thein SL, Rees DC.
Prenat Diagn 2007;27:104-10. -
Placental ABCA1 expression is reduced in primary antiphospholipid syndrome compared to pre-eclampsia and controls.
Albrecht C, Soumian S, Tetlow N, Patel P, Sullivan MH, Lakasing L, Nicolaides K, Williamson C.
Placenta 2007;28:701-8. -
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis.
Yu CKh, Casas JP, Savvidou MD, Sahemey MK, Nicolaides KH, Hingorani AD.
BMC Pregnancy Childbirth 2006;6:7. -
Noninvasive prenatal detection of fetal trisomy 18 by epigenetic allelic ratio analysis in maternal plasma: theoretical and empirical considerations.
Tong YK, Ding C, Chiu RW, Gerovassili A, Chim SS, Leung TY, Leung TN, Lau TK, Nicolaides KH, Lo YM.
Clin Chem 2006;52:2194-202. -
Cell-free DNA levels in pregnancies at risk of sickle-cell disease and significant ethnic variation.
Gerovassili A, Nicolaides KH, Thein SL, Rees DC.
Br J Haematol 2006;135:738-41. -
Detection of trisomy 21 by quantitative mass spectrometric analysis of single-nucleotide polymorphisms.
Tsui NB, Chiu RW, Ding C, El-Sheikhah A, Leung TN, Lau TK, Nicolaides KH, Lo YM.
Clin Chem 2005;51:2358-62. -
Comparison of protocols for extracting circulating DNA and RNA from maternal plasma.
Chiu RW, Lui WB, El-Sheikhah A, Chan AT, Lau TK, Nicolaides KH, Lo YM.
Clin Chem 2005;51:2209-10. -
Placental expression of IFN-gamma and its receptor IFN-gammaR2 fail to switch from early hypoxic to late normotensive development in pre-eclampsia.
Banerjee S, Smallwood A, Moorhead J, Chambers AE, Papageorghiou A, Campbell S, Nicolaides K.
J Clin Endocrinol Metab 2005;90:944-52. -
Uterine artery Doppler and mid-trimester maternal plasma homocysteine in subsequent pre-eclampsia.
Yu CK, Lakasing L, Papageorghiou AT, Spencer K, Nicolaides KH.
J Matern Fetal Neonatal Med 2004;16:134-9. -
Evaluation of human chorionic gonadotropin beta-subunit mRNA concentrations in maternal serum in aneuploid pregnancies: A feasibility study.
Ng EK, El-Sheikhah A, Chiu RW, Chan KC, Hogg M, Bindra R, Leung TN, Lau TK, Nicolaides KH, Lo YM.
Clin Chem 2004;50:1055-7. -
Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia.
Savvidou MD, Hingorani AD, Tsikas D, Frolich JC, Vallance P, Nicolaides KH.
Lancet 2003;361:1511-7. -
First-trimester maternal serum PAPP-A, SP1 and M-CSF levels in normal and trisomic twin pregnancies.
Bersinger NA, Noble P, Nicolaides KH.
Prenat Diagn 2003;23:157-62. -
Platelet changes and subsequent development of pre-eclampsia and fetal growth restriction in women with abnormal uterine artery Doppler screening.
Missfelder-Lobos H, Teran E, Lees C, Albaiges G, Nicolaides KH.
Ultrasound Obstet Gynecol 2002;19:443-8. -
Endothelial nitric oxide synthase gene polymorphism and maternal vascular adaptation to pregnancy.
Savvidou MD, Vallance PJ, Nicolaides KH, Hingorani AD.
Hypertension 2001;38:1289-93. -
Vasoactive mediator release by fetal endothelial cells in intrauterine growth restriction and preeclampsia.
Parra MC, Lees C, Mann GE, Pearson JD, Nicolaides KH.
Am J Obstet Gynecol 2001;184:497-502. -
Maternal serum S100 protein in normal and Down syndrome pregnancies.
Abraha HD, Noble PL, Nicolaides KH, Sherwood RA.
Prenat Diagn 1999;19:334-6. -
Carbonic anhydrase isoenzymes CAI and CAII in semen, decidua, chorionic villi and various fetal tissues.
Ali Akbar S, Nicolaides KH, Brown PR.
Early Hum Dev 1998;10;51:205-11. -
First trimester urine free beta hCG, beta core, and total oestriol in pregnancies affected by Down's syndrome: implications for first-trimester screening with nuchal translucency and serum free beta hCG.
Spencer K, Noble P, Snijders RJ, Nicolaides KH.
Prenat Diagn 1997;17:525-38. -
Urinary beta-core hCG: screening for aneuploidies in early pregnancy (11-14 weeks gestation)
Macintosh MC, Nicolaides KH, Noble P, Chard T, Gunn L, Illes R.
Prenat Diagn 1997;17:401-5.